PRODUCT DETAILS

About Cyendiv 100mg Soft Gelatin Capsule

NINTEDANIB belongs to the category of 'anti-fibrotic medicine' and it is primarily used to treat idiopathic pulmonary fibrosis (IPF) in adults. IPF is an irreversible disease that is marked by a progressive decline in lung function. The tissues in the lungs become swollen and scarred over time, due to which it gets difficult to breathe deeply. The scarring makes it hard for the lungs to work properly.

NINTEDANIB contains ‘Nintedanib’, which helps in reducing the scarring and swelling in the lungs by decreasing the release/activity of naturally occurring growth factors in the body, thereby helps you breathe better. NINTEDANIB helps in slowing down the progress of idiopathic pulmonary fibrosis.

Uses of Cyendiv 100mg Soft Gelatin Capsule

• Idiopathic pulmonary fibrosis

Medicinal Benefits of Cyendiv 100mg Soft Gelatin Capsule

NINTEDANIB is an anti-fibrotic medicine used to treat idiopathic pulmonary fibrosis (IPF) in adults. NINTEDANIB can help in effectively slowing down the rate of lung function decline by 50%. NINTEDANIB helps reduce the scarring and swelling in the lungs by decreasing the release/activity of naturally occurring growth factors in the body, thereby helps you breathe better. NINTEDANIB helps in slowing down the progress of idiopathic pulmonary fibrosis.

Directions for Use

Always use this medicine exactly as your doctor has told you or as per the package leaflet. You must keep to your doctor's instructions to get the maximum benefit.

Side Effects of Cyendiv 100mg Soft Gelatin Capsule

• Diarrhoea
• Feeling and being sick
• Tummy (Abdominal) Pain
• Loss of appetite and weight loss

Similar Drugs

For informational purposes only. Consult a doctor before taking any medicines.

In-Depth Precautions and Warning

Drug Warnings

• If you have or ever had liver, kidney and heart problems;
• If you take blood-thinning medicines (such as warfarin, phenprocoumon or heparin) to prevent blood clotting, or have or ever had bleeding problems;
• If you have recently had surgery. It may affect the way your wounds heal. Therefore, your treatment with NINTEDANIB will usually be stopped for a while if you have surgery. Your doctor will decide when to resume your treatment with this medicine;
• If you have abnormally high blood pressure in the blood vessels of the lungs (pulmonary hypertension);
• If you have or have had an aneurysm (enlargement and weakening of a blood vessel wall) or a tear in a blood vessel wall;
• Inform your doctor or pharmacist if you are taking, have recently taken or might take any other medicines, including herbal medicines and medicines obtained without a prescription.

Drug Interactions

Drug-Drug Interaction:

NINTEDANIB may have interaction with medicines used to treat fungal infections (e.g. ketoconazole), medicines used to treat bacterial infections/CYP3A4 inhibitors (e.g. erythromycin), medicines that affect your immune system (e.g. cyclosporine), antibiotic medicines used to treat tuberculosis (e.g. rifampicin), medicines to treat seizures (e.g. carbamazepine, phenytoin), and herbal medicines to treat depression (e.g. St. John’s Wort).

Drug-Disease Interaction:

 NINTEDANIB may interact with smoking, severe hepatic and end-stage renal impairment requiring dialysis.

Safety Advice

ALCOHOL

It is not known if alcohol interacts with NINTEDANIB. However, as a precautionary measure, you are recommended not to consume alcohol along with NINTEDANIB to avoid unpleasant side effects.

PREGNANCY

NINTEDANIB is listed as pregnancy category D. Because NINTEDANIB can cause harm to the fetus, women of childbearing potential should be advised to avoid becoming pregnant while receiving treatment with NINTEDANIB.

BREAST FEEDING

Consult your doctor if you are breastfeeding; your doctor will decide whether NINTEDANIB can be taken by breastfeeding mothers or not.

DRIVING

NINTEDANIB may have a minor influence on your ability to drive and use machines. You should not drive or use machines if you feel sick.

LIVER

Dose adjustment may be needed. NINTEDANIB is not recommended for patients with severe hepatic impairment. Please consult your doctor if you have a liver impairment or any concerns regarding this.

KIDNEY

Dose adjustment may be needed. NINTEDANIB is not recommended for patients with an end-stage renal disease requiring dialysis. Please consult your doctor if you have kidney impairment or any concerns regarding this.